A lack of connections between parts of the brain involved in emotional, sensory and cognitive processes may be linked to suicide risk | The study of over 500 people found that people who were suicidal had decreased brain connectivity across 86 brain regions.

https://www.scimex.org/newsfeed/lack-of-brain-connections-may-be-linked-to-suicide-risk

3 Comments

  1. From the [study](https://www.nature.com/articles/s44220-024-00325-y): Although suicide risk is a major public health issue, attempts to understand the neural basis of suicidality have been limited by small sample sizes and a focus on specific psychiatric disorders. This sample comprised 579 participants, of whom 428 had a psychiatric disorder (depression, anxiety or stress-related disorder) and 151 were non-psychiatric controls. All participants underwent structured clinical interviews, including an assessment of suicidality in the past month, and completed a functional magnetic resonance imaging scan. There were 238 (41.1%) participants who met criteria for suicidality and 341 (58.9%) were non-suicidal. Task-derived functional connectivity was calculated for 436 brain regions, comprising 8 intrinsic connectivity networks.

    Participants who were suicidal had decreased connectivity in a network of 143 connections across 86 brain regions. This pattern was characterized primarily by decreased connectivity within the visual, somatomotor and salience networks, between these networks, and also with the default mode and limbic networks. By adopting a transdiagnostic approach with a very large sample of individuals with mood disorders, anxiety and stress and non-psychiatric participants, this study highlights the hypoconnectivity that characterizes suicidality and points to altered connectivity within and between key networks involved in emotional, sensory and cognitive processes that are implicated in suicidal risk.

  2. Doesn’t adverse childhood events like sexual assault, physical assault, neglect mess up development of a healthy brain and therefore brain connections? Could this partly indicate why abuse survivors have increased risk of suicide?

  3. lochnesslover on

    I believe it, I think it’s a glitch, and when i am weak in other ways, lacking sleep, going through sever stress or other things it just glitches harder. It’s always been there. As far back as I remember