Science

New research has found that the effectiveness of ADHD medication may be associated with an individual’s neuroanatomy. These findings could help advance the development of clinical interventions

April 18, 2024

https://www.kcl.ac.uk/news/responsiveness-to-adhd-treatment-may-be-determined-by-neuroanatomy

View 3 Comments

3 Comments

giuliomagnifico on April 18, 2024 3:12 pm

>Researchers found that adults with ADHD who were not responsive to MPH had significant differences in their brain anatomy as compared to both those that responded and controls. These anatomical differences meant that their attention improved less when taking treatment.
>
>Some group differences between individuals with ADHD and controls were associated with differences in the expression of genes related to the transport of noradrenaline, a known target of ADHD medications.
>
>Though MPH is generally effective in improving ADHD symptoms, these findings may help researchers and clinicians understand previous randomised controlled trials which have reported that more than one third of adults do not respond to MPH.

Paper: [Cortical alterations associated with lower response to methylphenidate in adults with ADHD | Nature Mental Health](https://www.nature.com/articles/s44220-024-00228-y)
SAdelaidian on April 18, 2024 3:41 pm

>We only recruited males because ADHD is more commonly diagnosed in males. Nonetheless, we encourage future studies to extend our analyses to the female population with ADHD.
Consistent_Bread_V2 on April 18, 2024 3:46 pm

I wonder why some people (like myself) respond so much better to indirect agonists like adderall as opposed to reuptake inhibitors like Ritalin

New research has found that the effectiveness of ADHD medication may be associated with an individual’s neuroanatomy. These findings could help advance the development of clinical interventions

A proposed experiment could bring scientists closer to answering the long-standing question of whether gravity is a classical or a quantum phenomenon. If gravity is intrinsically quantum, the mutual gravitational attraction between the two objects could cause them to become entangled.

Researchers have discovered that an essential nutrient called choline is transported into the brain by a protein called FLVCR2. These findings could inform the future design of drugs for diseases such as Alzheimer’s and stroke.

A new study found that young women who took a social media break for as little as one week had a significant boost in self-esteem and body image – particularly those most vulnerable to thin-ideal internalization.

3 Comments

Tags

New research has found that the effectiveness of ADHD medication may be associated with an individual’s neuroanatomy. These findings could help advance the development of clinical interventions

Bytes Europe

A proposed experiment could bring scientists closer to answering the long-standing question of whether gravity is a classical or a quantum phenomenon. If gravity is intrinsically quantum, the mutual gravitational attraction between the two objects could cause them to become entangled.

Researchers have discovered that an essential nutrient called choline is transported into the brain by a protein called FLVCR2. These findings could inform the future design of drugs for diseases such as Alzheimer’s and stroke.

A new study found that young women who took a social media break for as little as one week had a significant boost in self-esteem and body image – particularly those most vulnerable to thin-ideal internalization.

3 Comments